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An Iranian couple living in the US become trapped inside a hotel when insidious events force them to face the secrets that have come between them, in a night that never ends.。布莱恩无意间被一个自称是脑魔的怪物附体，这种怪物所分泌出来的汁液能够让人获得至高无上的快乐，但同时也会带来地狱般的痛苦。布莱恩被脑魔折磨的死去活来，更要被迫杀人以便满足脑魔的日常需求……。有犯罪前科的艾美在一间旅馆上第一次夜班，不料十年前曾在此地发生过的一起骇人谋杀案，却将艾美受困在反覆目击恐怖事件的轮迴之中。她必须和昔日命案的受害者齐心协力，想办法摆脱嗜血如命的谋杀犯，并且尽可能拯救旅馆的住客。。