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In 1828 Scotland, Edinburgh surgeon Dr. Knox does medical research on cadavers he buys from murderers Burke and Hare, without questioning the unethical procurement methods.。Three sisters with quite different personalities and lives reunite when Babe, the youngest, has just shot her husband. Oldest sister Lenny takes care of their grandfather and is turning into an old maid. Meg, who aspires to make it in Hollywood as a singer and actress, has had a wild, man-filled life. Their reunion is joyful but also stirs up much tension.。